PS09-Sol - Genetics 320, Problem Set Nine (15 points) 1 (2...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Genetics 320, Problem Set Nine (15 points) 1 (2 points) : Consider a locus with four alleles ( A 1 to A 4 ) at the following frequencies: p 1 = 0 . 1 , p 2 = 0 . 2 , p 3 = 0 . 3 , p 4 = 0 . 4 . Assume random mating and all other Hardy-Weinberg conditions. What is the frequency of (a) A 2 A 3 ? 2 p 2 p 3 = 0 . 12 (b) A 4 A 4 ? p 2 4 = 0 . 16 (c) All heterozygotes involving allele A 2 ? 2 p 2 (1- p 2 ) = 0 . 32 (d) All heteroyzgotes? 1- ( p 2 1 + p 2 2 + p 2 3 + p 2 4 ) = 0 . 70 (e) Of a mating between A 1 A 2 and A 3 A 3 parents. Prob( A 1 A 2 ) = 2 p 1 p 2 = 0 . 04 , Prob( A 3 A 3 ) = p 2 3 = 0 . 09 , Hence, Prob( A 1 A 2 A 3 A 3 mating) = Prob( father = A 1 A 2 , mother = A 3 A 3 ) + Prob( father = A 3 A 3 , mother = A 1 A 2 ) = 2 (0 . 04 . 09) = 0 . 0072 . 2 (2 points) : Let p (0) = freq( A ) in the initial generation (which we call generation 0). As- suming Hardy-Weinberg conditions: (a) What is the frequency of AA homozygotes in the next generation (generation 1)? p (0) 2 (b) What is the frequency of heterozygotes involving A in generation 1? 2 p (0) [ 1- p (0) ] (b) Given these genotype frequencies, show that p (1) = freq( A in generation 1) = p (0) . p (1) = freq( AA in gen 1) + (1/2)freq( Aa in gen 1) = p (0) 2 + (1 / 2)2 p (0) [ 1- p (0) ] = p (0) 2 + p (0)- p (0) 2 = p (0) 3 (2 points) : This problem examines what happens when there are different allele frequencies in the two sexes (as would occur if one mates males from one population with females from a second). Assume an autosomal locus, where the frequency of allele A in the male and female founding populations is p and r , respectively. Assuming all other Hardy-Weinberg conditions hold, (a) What is the frequency of AA homozygotes in their offspring? p r (b) What is the frequency of A- heterozygotes? p (1- r ) + (1- p ) r (c) What is the frequency of allele A in their male offspring? In their female offspring?...
View Full Document

This note was uploaded on 12/09/2009 for the course ECOL UNIVERSITY taught by Professor Walsh during the Spring '09 term at University of Arizona- Tucson.

Page1 / 4

PS09-Sol - Genetics 320, Problem Set Nine (15 points) 1 (2...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online