Linkage - Linkage Key Concepts Excess of parental gametes Allows for ordering of genes along a chromosome Linkage phase Coupling vs repulsion

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Linkage: Key Concepts • Excess of parental gametes • Allows for ordering of genes along a chromosome • Linkage phase – Coupling vs. repulsion • Recombination frequency, c – c = frequency of recombinant gametes – Estimating the recombination frequency • Computing genotype frequencies Linkage • When genes are on the same chromosome, they can show departures from independent assortment • If genes on the same chromosome are sufficiently far apart, they can segregate independently • Linkage allows for construction of a linkage maps (genetic map) Bateson and Punnet’s experiment • Bateson and Punnet performed a dihybrid cross in sweet pea • P- = purple flower, pp = red flower • L- = long pollen, ll = round pollen • Pure-breeding purple long crossed to a pure-breeding red round
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Thus PL and pl gametes (the parental gametes ) are over-represented, Pl and pL under-represented Note that P-L- and ppll over-represented. Suppose parent is PL/pl
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This note was uploaded on 12/09/2009 for the course ECOL 320 taught by Professor Weinert during the Spring '07 term at University of Arizona- Tucson.

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Linkage - Linkage Key Concepts Excess of parental gametes Allows for ordering of genes along a chromosome Linkage phase Coupling vs repulsion

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