IMG-1982.jpg - MEDICATION Clopidogrel CATEGORY CLASS Anti platelet REVIEW MODULE CHAPTER PURPOSE OF MEDICATION Expected Pharmacological Action

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Unformatted text preview: MEDICATION _ Clopidogrel CATEGORY CLASS_ Anti platelet REVIEW MODULE CHAPTER PURPOSE OF MEDICATION Expected Pharmacological Action Therapeutic Use Inhibits platelet aggregation by irrever- sibly inhibiting the binding of ATP to platelet Reduction in risk of MId stroke receptors. Complications Medication Administration Hypersensitivity to clopidogrel or prasugrel; Pathologic bleeding ( peptic ulcer, intracranial hemorrh- Recent MJ, stroke, or peripheral Arterial Disease age); Concurrent use of omeprazole or esomeprazole; Patients at risk for bleeding (trauma, suger surgery, or other PO: (Adults 75 my once daily pathologic conditions); History of GI Bleeding / ulcer disease, . Hepatic Severe Acute Coronary Syndrome Po: (Adults) 300 mg initially, then 75 mis once daily; aspirin Contraindications/Precautions 75- 325 ms once daily It siven concurrently should be GI Bleeding, abdominal pain, diarrhea, dyspepsia, gas- tritis Acute generalized exanthematous pustulosis, drug rash with eosinophillia and systemic Nursing Interventions Syptoms, Stevens- johnson syndrome, toxic epidermal necrolysis moniter patient for signs of throat pruritus, purpura, rash bleeding, neutropenia, Thrombotic Thrombocy. botic thrombocytic purpura. monitor bleeding Topenic purpura. time during therapy . Prolonged bleeding time , which is time and dose- dependent, is expected Monitor CBC w/differential Interactions and platelet count periodically during Concurrent ubciximab, eptifibatide, tirofiban, aspirin, therapy. Neutropenia and throm- NSAIDS, heparin, LMWHs, thrombolytic agents, SSRIS, bocytopenia may rarely occur SNRIS, prasugrel or warfarin may 1 risk of bleeding May & a metabolism and T effects of phenytoin, tolbutamide -tamoxifen , torsemide, fluvastation and many NSAID's, Client Education Advice pt to notify Health care Evaluation of Medication Effectiveness professional promptly if fever Prevention of stroke, MI, and vascular weakness, chills sore throat, rash, unusual bleedingor bruising, extreme death in patients at risk. Skin paleness, purple skin patches, Yellowing of skin or eyes, or neurological changes occur. ACTIVE I FARNING TEMPI ATFS THERAPEUTIC PROCEDURE...
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  • Fall '17
  • Platelet, Clopidogrel, Acute coronary syndrome, Evaluation of Medication Effectiveness

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