Unit 6 Molecular Movement

Unit 6 Molecular Movement - Membrane are full of proteins!...

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1 Unit 6 Part 3 Molecular Movement Through Membranes Membrane are full of proteins! Sandwich model - 1935 proteins Phospholipid bilayer outside inside Proteins can be amphipathic Amphipathic proteins can integrate into the bilayer hydrophobic hydrophilic Membrane are full of proteins! Fluid-mosaic model outside inside proteins
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2 Figure 6-20 Outside cell Inside cell Peripheral membrane protein Integral membrane protein Peripheral membrane protein groups Molecular model of fatty acid tails H 2 O H 2 O fatty acid head groups fatty acid head Types of membrane proteins membrane Integral Peripheral Lipid anchored Integral membrane proteins alpha helix Beta sheet (rolled, β -barrel) Lipid bilayer
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3 Hydrophobic side chains hydrogen bonds h h h h h h h h h h h h h α -helical membrane spanning domain α -helical” transmembrane proteins aqueous pore amphipathic α -helix bilayer + + + + + + + + + + + hydrohobic hydrophilic α -helical” transmembrane proteins Photosynthetic reaction center of bacterium NOT a pore 2 subunits, each with 5 α -helices Notice the peripheral membrane proteins in complex!
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This note was uploaded on 12/10/2009 for the course MCDB 1150 at Colorado.

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Unit 6 Molecular Movement - Membrane are full of proteins!...

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