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2009 / Jul-Dec / Volume 4 / J Pediatr Neurosci / 61 DOI: 10.4103/1817-1745.57322 Online full text at http://www.pediatricneurosciences.com Original Article Meningiomas in children: A study of 18 cases Nirav Mehta, Sanat Bhagwati, Geeta Parulekar Department of Neurosurgery, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India Address for Correspondence: Dr. S. N. Bhagwati, Room No. 129, 1st Floor, MRC, Bombay Hospital, 12 New Marine Lines, Mumbai: 400020, Maharashtra, India. ABSTRACT Background: Background: Intracranial meningiomas are rare tumors in children accounting for 0.4-4.6% of all primary brain tumors in the age group of 0-18 years. Objective: Objective: To retrospectively analyze the epidemiological profile, clinical features, radiological findings, type of excision, histopathological findings, and overall management profile of these patients. Materials and Materials and Methods: Methods: Eighteen consecutive cases of meningioma in patients under 18 years of age admitted and operated at our institute between the years 1974-2005 were included in this study. Results: Results: The mean age of patient at presentation to our hospital was 12.81 years. The male to female ratio was 1.57:1. The median preoperative duration of symptoms was 1.2 years. An increased incidence was seen in patients with neurofibromatosis. Intraventricular and skull base locations were common. Total tumor excision was achieved in all cases. Conclusion: Conclusion: A higher incidence of atypical and aggressive meningiomas is seen in children. Children with complete resection and a typical benign histology have a good prognosis. Key words: Key words: Meningioma, childhood meningioma, pediatric neoplasms, neurofibromatosis Introduction Meningiomas occur most commonly in the fifth decade of life, accounting for approximately 15-20% of primary intracranial tumors. [1] Intracranial meningiomas in children and adolescents are rare tumors. In most large series, the incidence of meningiomas before the age of 16 years ranges from 0.4 to 4.6% of all primary brain tumors in this age group. [2-7] They account for 0.9-3.1% of all intracranial meningiomas. [8-10] The female preponderance found in adult patients is not seen in children, the reported male- to-female ratio in children being 1.2:1. [1,11] Risk factors for the development of meningiomas include the diagnosis of neurofibromatosis type two (NF-2) and a history of radiation therapy, the so-called radiation- induced meningiomas. [12] Meningiomas in children have been considered by some to be more aggressive than their adult counterparts. [13-16] Materials and Methods Eighteen consecutive cases of meningioma in patients under 18 years of age admitted and operated at Bombay hospital institute of medical sciences, Mumbai, India, by senior author (Dr. SNB) between the years 1974-2005 were included in this study. All cases were confirmed by radiological, operative, and histopathological findings. We have tried to retrospectively analyze the epidemiological profile, clinical features, radiological findings, type of excision, histopathological findings, and overall management profile of these patients.
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