lecture_2

lecture_2 - 1 Lecture 2 outline(1 Review of mitosis and...

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1 1 Lecture 2 outline (1) Review of mitosis and meiosis (2) Agreement between chromosome behavior during meiosis and behavior of Mendel’s genes. (3) Use of the product rule in computation of segregation ratios. (4) Sex chromosomes (5) Gene dosage compensation (6) Sex linkage (7) Proof of chromosome theory of inheritance (8) Human pedigree analyses: segregation of an autosomal dominant gene, autosomal recessive gene, X-linked recessive gene (9) An axample of pedigree analysis
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2 2 Mitosis is a conservative process Cell cycle: G 1 , S, G 2 , and mitosis G1 G2 Mitosis (anaphase) Daughter nuclei Mitosis: prophase, metaphase, anaphase, telophase (Look up the chromosome behavior during these stages on p. 47 in your book)
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3 3 Meiosis Meiosis I (= reductional division) Stages : Leptotene: chromosomes attach themselves by telomeres to the inner membrane of nuclear envelope. Lateral (axial) elements (of synaptonemal complex) are formed. Zygotene: homologues pair at their telomeres and begin to synapse forming the synaptonemal complexes. Pachytene : pairing ( synapsis ) is completed and crossing over is executed. Diplotene : homologous chromosomes are beginning to repulse each other, chiasmata form. Diakinesis
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lecture_2 - 1 Lecture 2 outline(1 Review of mitosis and...

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