Exam 3 Fall 2009 - Answers

Exam 3 Fall 2009 - Answers - Principles of Drug Action (BIO...

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Principles of Drug Action (BIO 365) Test #3 Name:_____________________________ November 25, 2009 Each of the 14 multiple choice questions is worth 0.75 marks out of 30 . The multiple choice questions are worth a total of 10.5 points out of 30, so budget your time appropriately. 1. Which one of the following statements is FALSE ? A. The same teratogen can produce different teratogenic effects if exposure occurs at different times during development. B. Exposure of a blastocyst to a teratogen is likely to lead to structural malformations. C. Learning disabilities, permanent alterations in certain biochemical pathways or changes in organ, immune or sexual function are examples of functional teratological abnormalities. D. Lipophilic teratogens may cause birth defects long after the mother’s exposure to the teratogen. E. Animal testing is not necessarily a reliable predictor of teratogenicity in humans because of species variability in teratogen sensitivity. 2. Most functional abnormalities caused by teratogens generally occur A. In the blastocyst period of development B. In the embryonic period of development. C. In the fetal period of development. D. During a period of great susceptibility just after fertilization. E. During the blastocyst and fetal periods of development. 3. Which one of the following statements is FALSE ? A. Negative reinforcement decreases the probability of a behaviour (eg. lever pressing) being expressed. B. Punishment has the opposite effects on the frequency of lever pressing, compared to negative reinforcement. C. Punishment decreases operant responding (eg. lever pressing). D. An FI 10 schedule means the rat must wait at least 10 seconds before his pushing the lever will again result in the release of a food pellet. E. An FR 10 schedule, in which the rat must press the lever 10 times before expecting a food reward, is an example of positive reinforcement. 4. Which one of the following statements is TRUE ? A. The elevated plus maze is used to model depression in rodents. B. Olfactory bulbectomy is used as a model for schizophrenia. C. Tetrahydrocannabinol (THC) and LSD are self-administered by rats. D. Because of its relatively high prevalence, schizophrenia is well understood and accurately modeled in rodents. E. The relative abuse potentials of different drugs can be measured using the progressive-ratio method of studying reinforcement. 5.
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This note was uploaded on 12/14/2009 for the course BIO 51310 taught by Professor Sisson during the Spring '08 term at University of Texas.

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Exam 3 Fall 2009 - Answers - Principles of Drug Action (BIO...

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