BLG 311-LECTURE-WEEK 3-Membrane-STUDENT.pptx - BLG 311 CELL BIOLOGY WEEK 3 MEMBRANE STRUCTURE(Chapter 10 Dr Hossein Noyan BLG311 Required Text Alberts B

BLG 311-LECTURE-WEEK 3-Membrane-STUDENT.pptx - BLG 311 CELL...

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BLG 311: CELL BIOLOGY WEEK 3 MEMBRANE STRUCTURE (Chapter 10) Dr. Hossein Noyan Fall 2019
Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P. 2014. Molecular Biology of the Cell. 6 th edition. W.W. Norton & Company Inc. BLG311 Required Text 2
The Cell Membrane Encloses the cell and defines its boundaries Maintains the essential differences between the cytosol and the extracellular environment
A phosphatidylcholine The Parts of a Typical Phospholipid Molecule
Four Major Phospholipids in Mammalian Plasma Membranes
Glycolipids and Cholesterol
Phospholipids Spontaneously Form Bilayers
Packing Arrangements of Amphiphilic Molecules in an Aqueous Environment
and
Individual Lipid Molecules Diffuse Freely Within The Plane Of A Lipid Bilayer Flip-flop: phospholipid molecules in synthetic bilayers very rarely migrate from the monolayer or a leaflet on one side to that on the other.
The Fluidity of a Lipid Bilayer Depends on Its Composition The fluidity of cell membranes must be precisely regulated. Length of the hydrocarbon chains Saturated vs. Unsaturated Cholesterol Effect of temperature
Phase Separation in Artificial Lipid Bilayers Lipid rafts
Raft Domain
Lipid Droplets Are Surrounded by a Phospholipid Monolayer

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