Dis.Ques.6-key - Discussion questions 6 1. The following...

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Discussion questions 6 1. The following diagram shows a protein-coding gene and specifies the positions of its translational start and stop signals: Which of the following is correct? A) The upper strand is the template, with the carboxy terminus of the protein to the right B) The upper strand is the template, with the carboxy terminus of the protein to the left C) The lower strand is the template, with the carboxy terminus of the protein to the right D) The lower strand is the template, with the carboxy terminus of the protein to the left E) Either strand could be the template on the basis of this information 2. A tRNA with the anticodon 3'–ACC–5' would carry the amino acid A) phenylalanine B) tyrosine C) serine D) threonine E) tryptophan 3. All of the following are general purpose translation components and could be used in the translation of any gene, except for one. Which one? A) tRNA B) rRNA C) mRNA D) methionine E) initiation factors 4. What would the minimum word (codon) size be to encode all 20 amino acids if the number of different bases in the mRNA were (a) two? (b) three? (c) five? Give your reasoning. Assume that all other features of the translation of mRNA into protein are the same as what we now know. No. of bases Word size Number of combinations (a) 2 5 2 5 = 32 (b) 3 3 3 3 = 27 (c) 5 2 5 2 = 25 Note: The number of combinations must be 21 (20 amino acids and one stop codon).
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5. One early piece of evidence that the genetic code is non-overlapping was the observation that hemoglobin mutants that had amino acid substitutions always had a single amino acid substituted. The first 8 amino acids in the normal human beta chain
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This note was uploaded on 12/17/2009 for the course BIO Genetics taught by Professor Saxena during the Spring '08 term at University of Texas at Austin.

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Dis.Ques.6-key - Discussion questions 6 1. The following...

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