Quiz 6 2009 WED-KEY - BIO325 Genetics Instructor Dr Tracey...

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BIO325 Genetics Instructor: Dr. Tracey Ruhlman TA: Teofil Nakov QUIZ 6 Points are given in parentheses after each question. Total points = 20. 1. a) Explain the difference between the development toolkit genes (say HOX genes) and housekeeping genes. (3 points) The housekeeping genes are responsible for normal functioning of any cell. They are constitutively expressed no mater of the cell type, time in development, location in the organsms . ... (example RNA polymerase). Developmental toolkit genes on the other hand are expressed only at certain times and places in the embryo during development. b) One of the first steps in comparative genomics is to identify related genes called homologs. Explain the difference between orthologs and paralogs. (3 points) General definition is: Homology is similarity due to common ancestry. If two genes are similar in sequence or function because they originated as a result of a speciation event from a common ancestor, then they are orthologous to each other (eg. globin gene in mouse
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Quiz 6 2009 WED-KEY - BIO325 Genetics Instructor Dr Tracey...

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