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LECTURE_REVIEW_wk3 - regulated What are the three different...

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BICD110 SSII 09 Review -Week 3 Below are important points to know from week 3 lectures. However, please keep in mind, this list is not all inclusive. - What are the types of cell-cell communication? - What is the difference between paracrine and autocrine signaling? - What are the main components of signaling pathways? - Two types of receptors are involved in signaling. What are they? - Different cells can respond differently to the same signaling molecule. Give an example of such a molecule and the different responses it elicits. - Why is signaling important? - What type of cell-cell communication is slow and gradual? What type is fast? - How do intracellular receptors work? - Many mediators in signaling pathways act as molecular switches that alternate between active and inactive states. Discuss the two ways these molecular switches can be
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Unformatted text preview: regulated. - What are the three different types of receptors involved in cell signaling? - What are the steps involved in G-protein signaling? - What would happen if the GTP on the G& could not be hydrolyzed? - What are the different types of G proteins and where do they bring about effects? - How does G-protein signaling work? What is the effector and what are the secondary messengers? - What is PKA and how does it get activated in a G-protein pathway? - Gq stimulates a different effector and brings about a different response than G& . What is the effector and what is the downstream effect? - Ca 2+ acts as an effective secondary messenger because it is normally kept at a low concentration inside the cell. What keeps the intracellular Ca 2+ levels low? - How are the signaling pathways turned off?...
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