Pharmacotherapy & Drug Interactions

Pharmacotherapy & Drug Interactions - Exam 1...

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Exam 1 Chapter Notes PHARMACOTHERAPY 1) For patients receiving concurrent MNT and pharmacotherapy, ADA recommends that care be provided by: (C) A team approach with dietetics professionals and other members of the healthcare team. 2) MNT and Pharmacotherapy are the most cost-effective ways to treat many diseases and their symptoms 3) When pharmacotherapy is necessary for certain diseases, MNT should be continued because concurrent use with pharmacotherapy may decrease the amount and/ or meds necessary to achieve optimal disease control. 4) A multidisciplinary team is a collaborative team of health care professionals with varied expertise, working to aid in the care of the patient. Benefits include improved patient safety and clinical outcomes and cost savings. 5) Current Procedural Terminology (CPT) Codes are important to registered dietitians because it allows them to be paid directly for their services. 6) High doses of Grapefruit/Grapefruit juice: -Compounds in grapefruit magnify the action of calcium channel blockers -Inhibits the metabolism of the meds and lipid lowering meds. (Statins) -Interferes with the intestinal cytochrome (P450 3 A4) -Increasing effectiveness of meds, but also increases the side effects -Can inhibit blood pressure meds (Can lower BP very significantly) -High doses of garlic or fish oil supplementation can: -Prolong bleeding time and enhance the action of anticoagulants such as Warfarin sodium (Coumadin), Vitamin E & K- All can thin bloods 7) The only two antiobesity medications currently approved for long term use are Sibutramine and Orlistat. -Sibutramine suppresses appetite and causes an increase in metabolic rate -Orlistat, a lipase inhibitor, reduces fat digestion and absorption. 8) Increasing physical activity and decreasing energy intake is considered the most effective and maintaining weight loss. 9) The major side effects of thiazide and loop diuretics (meds to treat hypertension) are known to cause a concurrent loss of sodium, potassium, calcium, magnesium and zinc. POTASSIUM SPARING DIURETICS: Spironolactone- Holds onto Potassium -Potassium sparing diuretics exchange potassium for sodium, resulting in an increase in serum potassium concentration and a need to monitor potassium intake to prevent
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hyperkalemia. (NEED low potassium diet and shouldn’t use salt substitutes made with potassium- Use MRS. DASH) LASIX: Diuretic -High potassium diet to monitor- No supplements -Salt substitutes are made with potassium chlorides- with high potassium diet can be too much 10) Patients taking calcium blockers should avoid grapefruits because they magnify the action of the medication 11) The first line of treatment for most individuals with elevated blood lipids is MNT.
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