BIO 325 - Fall 2009 - TTh 1230 to 200 - Exam 1 - Key-1

BIO 325 - Fall 2009 - TTh 1230 to 200 - Exam 1 - Key-1 -...

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GENETICS (BIO 325) Fall 2009 T, Th 12:30 – 2:00 PM section Key - Exam 1 __________________________________________________________________________________ 1. (a) Arginine and lysine are positively charged amino acids. This enables them to bind to the negatively charged phosphates in the backbone of the DNA helix. (b) scaffold heterochromatin centromere 2. Mitochondrial inheritance. The condition is passed on to all progeny of affected females but none of the progeny of affected males. III-1 through III-4 show that it cannot be a nuclear- encoded dominant gene. Since it is a rare disorder, we can assume that I-1, II-5, and II-7 are not carriers, therefore the disorder cannot be a nuclear-encoded recessive. 3. 4. Because the man's father was homozygous dominant for both gene pairs, the man's dominant alleles ( A and B ) must be in cis -configuration, and the man's mother contributed a chromosome with the recessive alleles in cis. The recombination frequency between these gene loci is 18%. So 18% of the father's gametes will be recombinant types, which includes two reciprocal products (9% Ab + 9% aB ). The mother produces only one kind of gamete ( ab ). For the first child to be Ab / ab
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BIO 325 - Fall 2009 - TTh 1230 to 200 - Exam 1 - Key-1 -...

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