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Problem set for midterm 2

Problem set for midterm 2 - I For each of the following...

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I. For each of the following groups of terms, circle the ONE TERM that DOES NOT FIT with the others. Then in ONE SENTENCE OR LESS , explain how the other three terms are related. (3 points each, 30 points total) a) Na+/K+ ATPase, oubain, symport, active transport oubain ; the other ones are all some type of transporting integral molecule on a membrane. Na+/K+ ATPase is an active phosphorylating antiport, carrying K+ into the cell and Na+ out of the cell. Symport is an active transporting protein that carries two substances (proteins) into or out of the cell and active transport is exactly what these antiport and symport work. Symport. Na+/K+ ATPase is an active transport pump, inhibited by oubain. b) passive transport, myosin, ATP hydrolysis, muscle contraction myosin causes muscle contraction through ATP hydrolysis. passive transport. The cycle that leads to muscle contraction involves actin, myosin, and ATP hydrolysis. c) glycogen, tetrahedral transition state, oxyanion hole, serine, glycogen; when a substance bind to a serine protease enzyme, such as chymotrypsin, it creates a tetrahedral transition state with aa of the enzyme, which is then stabilized by the oxyanion hole. . glycogen. All involved in catalytic mechanism of serine proteases d) ionophore, glucose transporter, aquaporin, F-actin f -actin; they are all transmembrane, and function in MB e) subtilisin, cholesterol, sphingomyelin, phosphatidylcholine subtilisin; rest is all membrane lipids. f) ABC transporter, trypsin, Na+/K+ ATPase, V-type ATPases trypsin: rest is active transporter. & membrane proteins g) amphipathic, phosphatdiylserine, membrane protein, catalysis catalysis; phosphatdiylserine is a type of phospholipids that are amphipathic, as are membrane protein.
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II. True/False a) __ f __ The lipid composition of all membranes of eukaryotic cells is essentially the same. Too general b) __ t __ Membrane proteins are sometimes attached to carbohydrates glycolipids – have glycogen attached to it .. glycogen = sugar = carbohydrate… c) __f_ The bilayer is stabilized by covalent bonds between neighboring lipid molecules d) __t__ Polar but uncharged compounds readily diffuse across the bilayer (not really Readily)… e) _ f __ Lipid fluidity in a bilayer is generally increased by a decrease in temperature high temp – fluidy bilayer (less saturated lipids), low temp – gel-like (semi-
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