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Unformatted text preview: 2 3. The first product of the reaction leaves a. Water enters and attacks carbonyl C 4. Second unstable intermediate formed a. Nucleophilic attack of water forms next negatively-charged tetrahedral transition state 5. Double bond reformed and enzyme regenerated a. Covalent bond between substrate C and Ser O is broken, releasing the second product...
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This note was uploaded on 01/02/2010 for the course BIBC BIBC 100 taught by Professor Buehler during the Fall '09 term at UCSD.
- Fall '09