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Unformatted text preview: enclosed in an ____________________ 3. __________________________ causes a conformational change in _______________________ 4. MB fusion occurs b Viral __________ released into cytoplasm Hemagglutinin (HA) o Structure (B&T Fig. 5.19) s Single polypeptide _____________________________ into HA1 & HA2 s Functions as ______________ on cell surface s 3 long helices tightly wrapped up (Motif: _______________________) s Receptor binding sites on _____________________________ s At the end of Helix A is ___________ peptide that is rich with ___________________ aa o Two Functions: Viral budding o The presence of sialic acid on the hosts cell plasma MB and viral surface can lead to problems s s Solution? Antigenic Drift vs. Antigenic Shift High pH Low pH...
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- Fall '09