{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

8-9th enantiomers - CM1012 Engineer Chemistry Chapter 9 in...

Info icon This preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon
1 CM1012 – Engineer Chemistry Chapter 9 in Burrow, Halman, Parsons, Pilling, Price ‘Carbon with chiral centre’ Dr Hai Deng Room 034 Meston Building Email: [email protected]
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Configurational isomers: isomers with chiral centres head2right any structure that has no plane of symmetry can exist as two mirror-image forms (enantiomers) head2right any structure with a plane of symmetry cannot exist as two enantiomers
Image of page 2
Chirality and achirality in daily life hands are chiral (Greek: cheir ) feet are chiral (shoes too) gloves are chiral (apart from most lab gloves!) socks are not chiral (usually!)
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Configurational isomers: isomers with chiral centres head2right if a molecule contains one carbon atom carrying four different groups it will not have a plane of symmetry and must therefore be chiral head2right a carbon atom carrying four different groups is a stereogenic or chiral centre head2right A chiral molecule and its non-superimposable mirror image are special types of configurational isomers called enantiomers
Image of page 4
Optical activity: rotation of plane-polarized light polarimetry : observation of the rotation of plane-polarized light • rotation in a clockwise direction is given a positive value, rotation in an anticlockwise is a negative one checkbld enantiomers have different interactions with plane-polarized light;
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Properties of enantiomers head2right enantiomers have identical physical properties (e. g. melting points) head2right enantiomers have identical spectroscopical properties (e. g. UV, IR, NMR spectra, MS) head2right enantiomers cannot be separated by conventional chromatographic techniques (e. g. TLC, GC, HPLC) head2right single important exception: enantiomers rotate plane-polarized light in opposite directions
Image of page 6
Properties of enantiomers head2right enantiomers have identical physical properties (e. g. melting points) head2right enantiomers have identical spectroscopical properties (e. g. UV, IR, NMR spectra, MS) head2right enantiomers cannot be separated by conventional chromatographic techniques (e. g. TLC, GC, HPLC) head2right single important exception: enantiomers rotate plane-polarized light in opposite directions
Image of page 7

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Properties of enantiomers head2right If only one enaniomer is present, a sample is considered to be opitcally pure . head2right Racemate (Racemic mixture): an equal mixture of two enantiomers and can be designated as (±). head2right Racemization : a process that a pure enantiomer can be transformed into a racemate head2right Resolution : a process that a racemate can be separated into its component enantiomers.
Image of page 8
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern