BE230_Lecture_14 - Cell Structure & Function BE230 Dr...

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Cell Structure & Function BE230 Dr Christine Loscher Lecture 3 Hormones
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Signal Amplification Important aspect of a cell’s response to an external signal Often only extremely small amounts of the ligand are necessary to elicit a cell response BUT cell responds in quite a dramatic way (inititates a cascade of events – signal transduction) “it is like a fleeting scent or whispered phrase from someone you are attracted to – a tiny signal, but one that makes your cheeks flush and your heart pound”
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Signal Amplification Hypothetical signaling pathway At each step in the cascade, a signalling intermediate persists long enough to stimulate the production of many molecules required for the next step Eg. A single epinephrine ligand can elicit the production of hundreds of millions of glucose molecules 1 molecule 10 2 molecule 10 4 molecule 10 6 molecule 10 8 molecule
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Hormones Chapter 23 Movie
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Hormones Small and hydrophobic
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Hormones diffuse directly across the plasma membrane of target cells
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This note was uploaded on 01/05/2010 for the course FSH BT taught by Professor Ianmarison during the Fall '09 term at Dublin City University.

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BE230_Lecture_14 - Cell Structure & Function BE230 Dr...

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