BE230_Lecture_6 - BE230 Lecture 7 Neurons-Structure...

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BE230 Lecture 7 Dr Rosaleen Devery
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Àt end of this lecture You will know 1. What events are carried out at plasma membrane of neuron 2. How a neuron’s resting potential is measured 3. How a resting potential is generated 4. What an action potential is 5. How action potential is propagated 6. What happens in a synaptic cleft 7. Why neurotransmitters are excitatory and inhibitory 8. Describe main neurotransmitters 9. How medicinal drugs work 10.How recreational drugs work
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What are neurons? Functional units of nervous systems Structure permits neurons to receive and transmit information Structure of a motor neuron- note its features Cell body Numerous dendrites Single axon Myelin sheath Nodes of Ranvier Synaptic terminals Commands signals from your spinal cord to your skeletal muscle
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Supporting Cells (Glia) Essential for normal functioning of nervous system Eg schwann cell in PNS Oligodendrocytes in CNS Signal travels along myelinated axon by jumping from node to node…travels much faster than the long route along length of axon 150 m/sec (540 km/h)! If no myelin sheaths, signals would go at ~ 5 m/sec
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Multiple Sclerosis (MS) Gradual destruction of myelin Progressive loss of signal conduction, muscle control, brain function
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What signals do neurons convey? What is a resting neuron? What is membrane potential? Potential energy that can be used to send signals from one part of body to another Resides in an electrical charge difference across neuron’s plasma membrane Cytoplasm is negative Fluid outside is positive Opposite charges attract; membrane stores E More opposite charges…the more energy is stored Need voltmeter to measure strength of stored energy
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potential across its membrane Measuring a neuron’s resting potential Need microelectrodes connected to
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This note was uploaded on 01/05/2010 for the course FSH BT taught by Professor Ianmarison during the Fall '09 term at Dublin City University.

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BE230_Lecture_6 - BE230 Lecture 7 Neurons-Structure...

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