Lecture_21_Environ2 - Lecture 21 Environment 2 1 lb/day =...

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Unformatted text preview: Lecture 21 Environment 2 1 lb/day = 3500 kcals Evidence: Biological Theory of Eating 1. No feedback from fat has been identified 2. Biological signals are not specific for eating behavior 3. How do you account for VMH lesion induced hyperphagia? 4. How do you account for VMH stimulation induced anorexia? 5. How do you account for LH lesion induced anorexia? 6. How do you account for LH stimulation induced eating 7. Small yearly energetic error does not mean there is physiological regulation 8. Food deprivation does not necessarily cause overeating 9. Overeating does not necessarily cause under-eating Evidence: Biological Theory of Eating 1. No feedback from fat has been identified 2. Biological signals are not specific for eating behavior 3. How do you account for VMH lesion induced hyperphagia? 4. How do you account for VMH stimulation induced anorexia? 5. How do you account for LH lesion induced anorexia? 6. How do you account for LH stimulation induced eating 7. Small yearly energetic error does not mean there is physiological regulation 8. Food deprivation does not necessarily cause overeating 9. Overeating does not necessarily cause under-eating 10. Role of genetics Genetics Animal Genetics A. About 22 strains of genetically obese mice B. 6 strains of obese rats C. All have: 1. Higher food intake 2. Lower resting metabolic rate 3. Less active 4. Become diabetic 5. Many endocrine abnormalities 6. Sluggish sympathetic nervous function Family Studies Correlations parent-child 0 parents overweight .3 chance overweight 1 parent overweight .6 chance overweight 2 parents overweight .8 chance of overweight grandparent-child sibling-sibling 0.4 0.5 0.6 0.7 0.8 0.9 1 Body Weight Height Correlations Mono reared together Mono reared apart Dizygot reared together Sorensen, 1993 0.4 0.5 0.6 0.7 0.8 0.9 1 Body Weight Height Correlations Mono reared together Mono reared apart Dizygot reared together r = .7 r 2 = % total variance = 49% of total variance Sorensen, 1993 Evidence: Biological Theory of Eating 1. No feedback from fat has been identified 2. Biological signals are not specific for eating behavior 3. How do you account for VMH lesion induced hyperphagia? 4. How do you account for VMH stimulation induced anorexia? 5. How do you account for LH lesion induced anorexia? 6. How do you account for LH stimulation induced eating 7. Small yearly energetic error does not mean there is physiological regulation 8. Food deprivation does not necessarily cause overeating 9. Overeating does not necessarily cause under-eating 10. Role of genetics 11. Role of early development Early Development 1.Adipose cells remain fairly constant across a lifetime 2.Two kinds of obesity a.Hypertrophic Adult onset 1.Adipose cells remain fairly constant across a lifetime 2.Two kinds of obesity a.Hypertrophic Adult onset Early Development 1.Adipose cells remain fairly constant 1....
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Lecture_21_Environ2 - Lecture 21 Environment 2 1 lb/day =...

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