Lecture_26_Protein_Malnutrition

Lecture_26_Protein_Malnutrition - Lecture 26 Protein...

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Unformatted text preview: Lecture 26 Protein Malnutrition 1. Malaria Prophylaxis- "Anemic" people are resistant to malaria- Iron supplementation increases the incidence of malaria 2. Low iron levels kill bacteria- cytokines release hepcidin from liver- hepcidin inhibits release of iron from cells Can Iron Supplementation be Harmful? Blood Transferin hepcidin liver cytokines 1. Malaria Prophylaxis- "Anemic" people are resistant to malaria- Iron supplementation increases the incidence of malaria 2. Low iron levels kill bacteria 3. Inflammation causes release of cytokines 4. Cytokines release hepcidin from liver 5. Hepcidin inhibits release of iron from cells 6. High blood iron correlated with increase in cardiovascular disease- Increased rate of oxidation of LDL 7. Giving Blood lowers risk of CVD Can Iron Supplementation be Harmful? Other Anemias normal Iron deficiency anemia Megaloblastic Anemia Red Blood Cell Division PRECURSOR TO RED BLOOD CELL Folate Adequate Normal Cell Division Red Blood Cells Red Blood Cell Division Within bone marrow PRECURSOR TO RED BLOOD CELL Folate Inadequate Cell unable to divide Macrocyte Megablastic Anemia is caused by: 1.Folic Acid Deficiency 2.B 12 Deficiency methionine homocysteine cysteine B 6 folic acid + B 12 Atherosclerosis and heart disease Folic Acid Deficiency Neural Tube Defect: Spinal Bifida Folic Acid Deficiency Folic Acid Fortification of Foods?...
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Lecture_26_Protein_Malnutrition - Lecture 26 Protein...

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