Lec 6 - Evolutionary Forces 9/9/9 Reading: Frisancho Ch 3...

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Evolutionary Forces 9/9/9 Reading: Frisancho Ch 3 Office hour: Wed 11:10-12:00 Savage 317 or 312 email: zg27@cornell.edu
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Reading for discussion section: Freeman & Herron Ch14 Reading and homework are posted
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Introduction to Biology Introduction to Genetics (examples in the textbook) Hardy–Weinberg equilibrium and Population Genetics
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Microevolution vs. Macroevolution Microevolution : small-scale changes in allele frequencies from generation to generation (population genetics) Macroevolution biological evolution over many generations and on the origin of higher taxonomic categories (at or above the species)
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Evolution deals with the change in gene frequency of a population from generation to generation Females A ( p ) a ( q ) Males A ( p ) AA ( p ²) Aa ( pq ) a ( q ) Aa ( pq ) aa ( q ²) Hardy–Weinberg equilibrium Know how to calculate the expected frequencies for multiple alleles
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Females A1 ( p ) A2 ( q ) A3( r ) Males A1 ( p ) A1A1 (p²) A1A2 (pq) A1A3 (pr) A2 ( q ) A1A2 (pq) A2A2 (q²) A2A3 (qr) A3 ( r ) A1A3 (pr) A2A3 (qr) A3A3 (r²) p+q+r =1 Three alleles for one locus: A1 ( p ), A2 ( q ), A3 ( r ) Three-allele Hardy–Weinberg equilibrium
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Genotype Frequency A1A1 A2A2 A3A3 A1A2 2pq A2A3 2qr A1A3 2pr p² + q² + r² + 2pq + 2pr + 2qr = ( p+q+r)² = 1 Three-allele Hardy–Weinberg equilibrium
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Assumption for Hardy–Weinberg equilibrium : 1. No selection 2. No migration (gene flow) 3. Infinite population size 4. No mutation Forces to change the genetic frequency are the Violation of assumption
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This note was uploaded on 01/06/2010 for the course NS 2750 taught by Professor Haas&gu during the Fall '08 term at Cornell University (Engineering School).

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Lec 6 - Evolutionary Forces 9/9/9 Reading: Frisancho Ch 3...

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