Lec 11 - Neutral Evolution Natural Selection Reading...

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Neutral Evolution & Natural Selection Sep 21, 2009 Reading: Holsinger 2001 Freeman & Herron P251-264
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1. Genetic Drift revisited 2. Genetic diversity in different populations 3. Neutral evolutionary rate 4. Near-Neutral theory
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Genetic drift Genetic drift addresses the influence random chance has on the survival of alleles, due to the statistical effect
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Founder effect The effect of establishing a new population by a small number of individuals, carrying only a small fraction of the original population's genetic variation Can cause frequency difference between the original and the new populations Genetic drift
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Modern Evolutionary Synthesis , the New Synthesis , the Evolutionary Synthesis Genetics Evolution is gradual Population thinking Selection is overwhelmingly the main mechanism of change The Modern Synthesis
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Neutrality: all the genotypes at a locus have the same fitness (s), the condition is called selective neutrality Most evolutionary change is the result of genetic drift acting on neutral alleles Neutral theory of evolution
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Neutralist and selectionist models of molecular evolution Deleterious Deleterious Neutral Advantageous Neutralist Neutralist Selectionist
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