Lecture 17 - Lecture 17 Genomics The human nuclear genome...

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Lecture 17 Genomics
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The human nuclear genome viewed as a set of labeled DNA
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Bioinformatics : analyzing the information content of entire genomes including all types of genes and gene products as well as the regulatory elements of DNA and RNA that dictate expression patterns in a temporal and spatial manner. Comparative genomics : exploits both similarities and differences in the genomes, RNA, proteins, and regulatory regions of different organisms to infer how selection has acted upon these elements. Identification of conserved sequences can be used to identify orthologs among closely or distantly related organisms and to evaluate gene function. Functional genomics: employs a variety of experimental methods to understand gene function and delineate interacting genes and proteins involved in biological processes. Under the genomics umbrella:
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Genomics, the global analysis of genomes, relies on the availability of genome sequences! Improved technology has facilitated massive expansion of the public databases and hence the power of the genomics approach. As of today, GenBank (NCBI) contains sequence and map data from the whole genomes of over 1000 organisms. The genomes represent both
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