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54 - affected by NSAIDs their interaction with ancillary...

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Sheet1 Page 1 1. Gut. 2003 Apr 52(4):600-8. Non-steroidal anti-inflammatory drugs: overall risks and management. Complementary roles for COX-2 inhibitors and proton pump inhibitors. Hawkey CJ, Langman MJ. Division of Gastroenterology, Queen's Medical Centre, University Hospital Nottingham, Nottingham, UK. [email protected] Non-steroidal anti-inflammatory drugs (NSAIDs) are well recognised as causing peptic ulceration and ulcer complications. However, several critical issues, including the amount of both gastrointestinal and non-gastrointestinal disease
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Unformatted text preview: affected by NSAIDs, their interaction with ancillary risk factors, and how to optimise management in subgroups, remain poorly understood. In this article, strategies for subgroups that take account of non-specific gastrointestinal risks, minimisation of residual risk, and the importance of non-gastrointestinal toxicity are suggested, and areas for research identified. PMCID: PMC1773617 PMID: 12631678 [PubMed - indexed for MEDLINE]...
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