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68 - 1 Gut 1995 Aug;37(2:182-6 Morbidity and treatment in...

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Sheet1 Page 1 1. Gut. 1995 Aug 37(2):182-6. Morbidity and treatment in elderly patients surviving hospital admission with bleeding peptic ulcer. Hudson N, Faulkner G, Smith SJ, Logan RF, Hawkey CJ. Department of Medicine, University Hospital, Nottingham. Bleeding peptic ulcer in the elderly is associated with use of non-steroidal, anti-inflammatory drugs (NSAIDs) and aspirin, presenting a therapeutic dilemma for the treatment of survivors. To determine the longterm morbidity of patients surviving bleeding peptic ulcer and their treatment, with particular reference to NSAID use, this study followed up 487 patients aged over 60 years, who survived an episode of bleeding peptic ulcer in Nottingham during 1986 to 1991. Information was gathered by evaluation of general practitioner and hospital records, scrutiny of death certificates, and postal questionnaire to surviving patients. Of 487 patients surviving a bleeding peptic ulcer, 345 were alive at the follow up, a mean 34.2 months after discharge. Of these 201 (58%) had taken NSAIDs before their ulcer bleed (104 non-aspirin NSAIDs, 77 aspirin, 20 both).
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