30 - 1. Aliment Pharmacol Ther. 2007 Apr 15;25(8):907-12....

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Sheet1 Page 1 1. Aliment Pharmacol Ther. 2007 Apr 15 Introduction of newer selective cyclo-oxygenase-2 inhibitors and rates of hospitalization with bleeding and perforated peptic ulcer. Christensen S, Riis A, Nørgaard M, Thomsen RW, Sørensen HT. Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. sc@dce.au.dk BACKGROUND: Limited data exist on the impact of the introduction of newer selective cyclo-oxygenase-2 inhibitors into clinical practice in 1999 on overall non-steroidal anti-inflammatory drug use and hospitalization rates of complicated peptic ulcer disease at the population level. AIM: To examine these issues, we conducted a population-based study in western Denmark, within a population of 1.2 million. METHODS: All patients with perforated (n = 1488) or bleeding peptic ulcer (n = 6017) between 1996 and 2004 were identified in hospital discharge registries. We computed standardized annual hospitalization rates and hospitalization rate ratios using Poisson regression. Data on annual number of
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This note was uploaded on 01/10/2010 for the course NSA 1010 taught by Professor Ahobaishi during the Spring '09 term at ND State.

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30 - 1. Aliment Pharmacol Ther. 2007 Apr 15;25(8):907-12....

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