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PGY300Renallec4 - RENAL CLEARANCE PHYSIOLOGY 300 DR JOHN A...

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RENAL CLEARANCE PHYSIOLOGY 300 DR. JOHN A. KRASNEY
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Reading Chapter 19, pages 632-634. Renal Clearance Problems. Renal Practice Exam
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Renal Clearance Provides a non-invasive method for measuring the ability of the kidneys to handle solutes and water. Clearance measures: Glomerular Filtration Rate Tubular Reabsorption Tubular Secretion Renal Plasma Flow
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Concentration of a Solute Concentration of a solute (mg/ml) = amount (10 mg) / volume (10 ml) = 1 mg/ml. Rearranging: Volume (ml) = Amount (mg) / Concentration (mg/ml).
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Mass Balance in the Kidneys P x , a . RPF a = (P x , v . RPF v ) + (U x . V) P x , a, P x , v = plasma concentrations of x in renal artery and vein (mg/ml), respectively. RPF a, RPF v = renal arterial, venous plasma flows (ml/ min) U x = concentration of x in urine (mg/ml) V = urine flow rate (ml/min) U x . V= renal excretion rate of x (mg/min).
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The Fick Principle Blood flow (ml/min) = Amount of x taken up/min /( [x,a] - [x,v]). Rearranging: Amount of x taken up/min = Blood Flow (ml/min) .
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  • Fall '05
  • Krasney
  • renal plasma flow, Renal Clearance, Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na, Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na Na

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