PGY300Renallec4

PGY300Renallec4 - RENAL CLEARANCE PHYSIOLOGY 300 DR. JOHN...

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RENAL CLEARANCE PHYSIOLOGY 300 DR. JOHN A. KRASNEY
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Reading Chapter 19, pages 632-634. Renal Clearance Problems. Renal Practice Exam
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Renal Clearance Provides a non-invasive method for measuring the ability of the kidneys to handle solutes and water. Clearance measures: Glomerular Filtration Rate Tubular Reabsorption Tubular Secretion Renal Plasma Flow
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Concentration of a Solute Concentration of a solute (mg/ml) = amount (10 mg) / volume (10 ml) = 1 mg/ml. Rearranging: Volume (ml) = Amount (mg) / Concentration (mg/ml).
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Mass Balance in the Kidneys P x , a . RPF a = (P x , v . RPF v ) + (U x . V) P x , a, P x , v = plasma concentrations of x in renal artery and vein (mg/ml), respectively. RPF a, RPF v = renal arterial, venous plasma flows (ml/ min) U x = concentration of x in urine (mg/ml) V = urine flow rate (ml/min) U x . V= renal excretion rate of x (mg/min).
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The Fick Principle Blood flow (ml/min) = Amount of x taken up/min /( [x,a] - [x,v]). Rearranging: Amount of x taken up/min = Blood Flow (ml/min) .
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This note was uploaded on 01/10/2010 for the course PGY 300 taught by Professor Krasney during the Fall '05 term at SUNY Buffalo.

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PGY300Renallec4 - RENAL CLEARANCE PHYSIOLOGY 300 DR. JOHN...

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