PGY300Renallec6

PGY300Renallec6 - REGULATION OF ELECTROLYTE BALANCE...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
REGULATION OF ELECTROLYTE BALANCE PHYSIOLOGY 300 DR. JOHN A. KRASNEY
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
READING Chapter 20, pages 652-663 Animations: Electrolyte Homeostasis pages 1-32
Background image of page 2
Renal Handling of NaCl Kidneys filter 1,500 gm of NaCl per day. 99% is reabsorbed. Daily excretion of Na + is ~ 6 gm. Plasma [Na + ] = 145 mM
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Intake of NaCl On average, we ingest 9 gm of NaCl per day. This raises pOsm by 155 mOsm. In order to maintain pOsm at 300 mOsm/L we are required to ingest an additional one liter of water per day.
Background image of page 4
Salt Intake and Arterial Hypertension Intake of NaCl is critically related to arterial blood pressure. Ingestion of NaCl raises plasma volume that in turn raises arterial blood pressure. Chronic ingestion of NaCl is associated with arterial hypertension.
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
ALDOSTERONE
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
Aldosterone Aldosterone acts on Principal cells of the distal nephron (cortical distal tubule and collecting duct) to stimulate facultative Na + reabsorption and secretion of K + Water reabsorption does not follow Na
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/10/2010 for the course PGY 300 taught by Professor Krasney during the Fall '05 term at SUNY Buffalo.

Page1 / 26

PGY300Renallec6 - REGULATION OF ELECTROLYTE BALANCE...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online