Lecture _ 7 Respiratory Disease Fall 2007

Lecture _ 7 Respiratory Disease Fall 2007 - Lecture 7...

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Lecture # 7 Respiratory Disease
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1. Review 2. Obstructive Diseases 3. Restrictive Diseases Respiratory Disease
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Review – Control of Ventilation
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Sensors - Central Chemoreceptors
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Sensors - Peripheral Chemoreceptors
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1. Review 2. Obstructive Diseases 3. Restrictive Diseases Respiratory Disease
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Mechanism of obstruction Respiratory Diseases - Obstructive
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Chronic obstructive lung disease (COPD) is associated with an increase in airflow resistance 1. Emphysema 2. Chronic Bronchitis 3. Asthma Respiratory Diseases - Obstructive
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Emphysema - Enlargement of airspace with destruction to their walls Pathology - Tissue destruction with loss of capillaries - Loss of elastin (decrease elastic recoil of lung, increase compliance) - Decrease in small airways - Structural changes can be seen with naked eye Pathogenesis - Excessive amounts of enzymes released that destroy elastin - Smoking makes it worse Respiratory Diseases – Emphysema
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Respiratory Diseases - Emphysema
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Respiratory Diseases - Obstructive
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Chronic Bronchitis -
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