3. Midterm 1 Version B

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Unformatted text preview: York
BIOL
2040
Fall
2009
 
 Kelly
Midterm
1B
Oct
 Biology 2040 Midterm I Version B Oct. 9, 2009 / 8:30 – 9:20 am • This exam must be submitted with your scantron sheet to receive a grade. • Your student number and name must be CLEARLY written on this booklet and scantron sheet in order to receive a grade. • Your student number must be BUBBLED CORRECTLY on the scantron to receive a grade • All questions on this exam are multiple choice – there is NO pattern to the answers (e.g., c, a, b, b, a, d), so donʼt look for one! • Non-programmable calculators are PERMITTED. • If you complete the exam before the allotted time, raise your hand to identify yourself to the invigilator. • The invigilators and instructors will immediately RELOCATE anyone or SUSPEND the examination for any individuals who are suspected of academic dishonesty. Good Luck! Last name First Name Student Number York
BIOL
2040
Fall
2009
 
 Kelly
Midterm
1B
Oct
 Section
A:
Answer
the
following
by
filling
in
the
appropriate
response
on
your
scantron.
 1. You
have
midterm
version
B.
Fill
in
b
for
this
question!
 
 2. Height
in
humans
is
an
example
of
a
_____
trait.
 A. Continuous
 B. Polygenic

 C. Quantitative
 D. All
of
the
above
 
 3. You
are
trying
to
develop
true‐breeding
blue
hydrangeas,
but
the
plants
in
one
corner
of
your
garden
 consistently
turn
pink
 regardless
of
your
mating
strategy.

Which
of
the
following
would
you
suspect
 played
a
role
in
your
failed
breeding
plan?
 A. Incomplete
penetrance
 B. Variable
expressivity
 C. Multiple
genes
affecting
this
trait.
 D. Environmental
effects
 
 4. Which
of
the
following
doesn’t
have
to
be
a
characteristic
of
a
good
model
organism?
 A. Short
generation
time
that
allows
multiple
generations
to
be
examined
within
a
short
time.
 B. Possess
a
genome
that
is
closely
related
to
the
human
genome.
 C. Produce
large
numbers
of
offspring.
 D. Only
a
and
b
are
not
characteristics
of
a
model
organism.
 
 5. What
aspect
of
chromosome
behaviour
 most
clearly
accounts
for
Mendel’s
principle
of
independent
 assortment?
 A. Movement
of
sister
chromatids
to
opposite
poles
at
anaphase
II
of
meiosis.
 B. Movement
of
homologous
chromosomes
to
opposite
poles
at
anaphase
I
of
meiosis.
 C. Crossing
over
between
homologous
chromosomes
during
prophase
I
of
meiosis.
 D. Independent
alignment
of
different
homologous
pairs
on
the
metaphase
I
spindle.
 
 6. A
woman
with
a
mutation
in
a
gene
on
her
X‐chromosome
will
pass
it
on
to
 A. All
of
her
daughters.
 B. All
of
her
sons.
 C. Half
of
her
sons,
and
all
of
her
daughters.
 D. All
of
her
sons,
and
half
of
her
daughters.
 E. All
of
her
sons
and
daughters.
 
 7. What
information
cannot
be
obtained
from
an
individual’s
karyotype?
 A. The
ploidy
of
the
individual.
 B. The
types
of
chromosomes
present
in
the
individual.
 C. The
number
of
autosomes
in
the
individual.
 D. The
sequence
of
bases
of
a
particular
gene.
 
 
 
 
 York
BIOL
2040
Fall
2009
 
 Kelly
Midterm
1B
Oct
 8. Genes
 R
 &
 F
 are
 located
 on
 different
 chromosomes.
 
 A
 woman
 is
 heterozygous
 for
 both
 genes.

 Which
of
the
following
processes
would
generate
different
combinations
of
alleles
of
these
2
genes?
 A. Recombination
 B. Independent
assortment
 C. Sister
chromatid
segregation

 D. Segregation
 
 9. The
 somatic
 cells
 of
 males
 in
 the
 species
 Dragontis
 elementis
 contain
 only
 1
 pair
 of
 homologous
 chromosomes
 (D1
 and
 D2),
 and
 another
 chromosome
 without
 a
 homolog
 (chromosome
 C).
 Which
 chromosomal
combinations
are
most
likely
to
be
among
the
4
meiotic
products
from
a
single
cell?
 A. D1C,
D1C,
D2,
D2
 B. D1C,
D2C,
D1,
D2
 C. D1C,
D1C,
D2C,
D2C
 D. D1D1,
D2D2,
C,
C
 
 10. What
 is
 the
 probability
 that
 a
 gamete
 from
 an
 individual
 with
 the
 genotype
 L1L2T1T1M1M2
 will
 contain
all
maternally
derived
homologues?
 A. 1/6
 B. 1/3
 C. 1/4
 D. 1/8
 
 11. In
a
group
of
dragons
homozygous
for
an
allele
that
causes
a
reduced
number
of
facial
bristles
(stiff,
 coarse
hairs),
you
notice
that
the
number
of
bristles
ranges
from
about
half
the
normal
number
to
 only
a
few
bristles.
This
is
an
example
of
which
of
the
following?
 A. Incomplete
dominance
 B. Codominance
 C. Incomplete
penetrance
 D. Variable
expressivity
 E. Both
a
and
c.
 
 12. Which
of
the
following
is
true
about
pleiotropy?
 A. It
always
involves
two
or
more
genes.
 B. It
only
refers
to
the
F1
generation.
 C. It
includes
genetic
phenomena
such
as
epistasis.
 D. It
refers
to
the
effects
of
a
single
gene.
 E. Both
b
and
d.
 
 13. Long
 ears
 in
 rabbits
 are
 an
 autosomal
 dominant
 trait
 that
 exhibits
 30%
 penetrance.
 You
 cross
 a
 rabbit
 heterozygous
 for
 long
 ears
 with
 one
 that
 is
 homozygous
 for
 normal
 ears.
 What
 is
 the
 probability
that
their
first
offspring
will
have
long
ears?
 A. 0.5
 B. 0.3
 C. 0.25
 D. 0.15
 
 
 York
BIOL
2040
Fall
2009
 
 Kelly
Midterm
1B
Oct
 Below
 is
 a
 pedigree
 for
 the
 ability
 to
 read
 minds
 and
 applies
 to
 the
 next
 2
 questions.
 
 Darkly
 shaded
 symbols
 represent
 individuals
 that
 exhibit
 the
 ability
 to
 read
 minds.
 
 Assume
 that
 read
 minds
 is
 completely
penetrant.
 
 I 
 
 II 
 
 III ? ? 
 
 14. For
the
above
pedigree,
what
is
the
mode
of
inheritance
of
being
able
to
read
minds?
 A. Autosomal
recessive
 B. Autosomal
dominant
 C. X‐linked
recessive
 D. X‐linked
dominant
 
 15. What
is
the
probability
that
the
first‐born
in
generation
III
will
be
able
to
read
minds?
 A. 1/2
 B. 1/3
 C. 1/4
 D. 1/6
 
 16. Sasha
 is
 a
 carrier
 for
 the
 X‐linked
 disease
 muscular
 dystrophy
 (XDXd)
 and
 is
 also
 a
 carrier
 for
 the
 autosomal
recessive
disease
albinism
(Aa).

Sasha
produces
an
egg
that
has
the
A
allele
and
the
D
and
 d
alleles
of
the
muscular
dystrophy
gene.

Assuming
no
crossing
over,
what
can
you
conclude?
 A. The
gamete
has
a
normal
chromosomal
number.
 B. A
nondisjunction
event
occurred,
but
you
can’t
determine
when
it
occurred
during
meiosis.
 C. A
nondisjunction
event
occurred
in
Meiosis
I.
 D. A
nondisjunction
event
occurred
in
Meiosis
II.
 
 
 17. Snoots
 have
 a
 diploid
 chromosome
 number
 of
 8.
 How
 many
 different
 chromosome
 combinations
 can
normally
be
found
in
the
gametes
of
this
organism,
assuming
that
no
crossing
over
occurs?
 A. 2
 B. 4
 C. 8
 D. 16
 
 18. Which
of
these
pedigrees
illustrates
complementation?
Shaded
 A symbols
represent
affected
individuals.
 A. A B. B
 C. C
 C D. D
 
 York
BIOL
2040
Fall
2009
 
 Kelly
Midterm
1B
Oct
 
 19. Mark
 is
 a
 carrier
 for
 diastrophic
 dysplasia
 (Dd),
 an
 autosomal
 recessive
 disorder
 and
 has
 achrondroplasia,
which
is
an
 autosomal
dominant
trait
(Aa).

Dustina
is
also
a
carrier
for
diastrophic
 dysplasia
and
also
has
achrondroplasia.

AA
human
embryos
do
not
survive
beyond
the
first
few
cell
 divisions
and
the
allele
is
considered
recessive
lethal.

Mark
and
Dustina
want
to
have
a
child.
What
is
 the
probability
that
their
child
will
have
only
diastrophic
dysplasia?
 A. 0
 B. 1/4
 C. 1/6
 D. 1/12
 E. 1/16
 
 20. In
 Snuffalufagi,
 height
 is
 controlled
 by
 the
 H
 gene;
 HH
 and
 Hh
 individuals
 have
 long
 legs
 and
 hh
 individuals
have
short
legs.

If
the
growth‐promoting
allele
(G)
is
absent,
there
is
very
limited
growth,
 regardless
 of
 which
 alleles
 are
 present
 at
 gene
 H
 and
 the
 Snuffalufagi
 have
 short
 legs.
 
 A
 cross
 is
 made
 between
 a
 true‐breeding
 long‐legged
 Snuffalufagi
 and
 a
 short‐legged
 Snuffalufagi
 that
 is
 homozygous
recessive
for
both
genes.

What
proportion
of
the
F2
progeny
will
have
short
legs?
 A. 1/16
 B. 3/16
 C. 7/16
 D. 9/16
 E. 1/4
 
 21. Three
mutant
strains
of
white
Smurfs
have
been
identified
and
all
are
true‐breeding.
When
strain
A
 was
crossed
with
strain
 C,
all
F1
Smurfs
were
 the
wild‐type
 blue
colour.
When
strains
 A
 and
 B
were
 mated,
all
the
progeny
were
white,
and
when
B
and
C
were
crossed,
all
the
progeny
were
blue.
What
 is
the
best
explanation
for
this
observation?
 A. B
and
C
have
mutations
in
the
same
gene,
and
A
has
a
mutation
in
a
different
gene.
 B. A
and
C
have
mutations
in
the
same
gene,
and
B
has
a
mutation
in
a
different
gene.
 C. A
and
B
have
mutations
in
the
same
gene,
and
C
has
a
mutation
in
a
different
gene.
 D. A,
B
and
C
are
all
mutations
in
the
same
gene.
 E. A,
B
and
C
are
all
mutations
in
different
genes.
 
 22. In
 Drosophila,
 forked
 bristles
 is
 a
 recessive
 sex‐linked
 trait,
 while
 purple
 eyes
 is
 an
 autosomal
 recessive
 trait.
 
 The
 wild‐type
 for
 each
 are
 straight
 bristles
 and
 red
 eyes,
 respectively.
 
 A
 female,
 heterozygous
 for
 both
 pairs
 of
 alleles,
 is
 mated
 with
 a
 male
 with
 forked
 bristles
 and
 purple
 eyes.
 What
proportion
of
the
daughters
will
have
forked
bristles
and
purple
eyes?
 A. All
 B. 3/4
 C. 1/2
 D. 1/4
 E. None
 
 York
BIOL
2040
Fall
2009
 
 Kelly
Midterm
1B
Oct
 AB 23. The
 genes
 I ,
 I 
 and
 i
 contribute
 to
 the
 ABO
 blood
 antigens
 in
 humans.
 In
 another
 trait,
 Rh+
 is
 dominant
to
Rh‐.
If
a
mother
with
phenotype
A
Rh+
has
a
child
with
a
phenotype
of
O
Rh+,
which
one
 of
the
following
genotypes
is
not
possible
for
the
father?
 A. IAi
Rh‐Rh‐
 B. IBi
Rh+Rh‐
 C. ii
Rh‐Rh‐
 D. ii
Rh+Rh‐
 E. IAIA
Rh+Rh+
 
 
 Section
B:
Answer
the
following
by
filling
in
the
blank
with
the
appropriate
response.
 
 24. Two
individuals
of
genotype
 RRSSTTYY
and
 rrssttyy
are
mated.
The
F1
generation
is
interbred
(self‐ fertilized)
 to
 yield
 1500
 progeny.
 
 What
 proportion
 of
 the
 F2
 is
 expected
 to
 be
 RrSSTtYy?

 ______________
 
 25. The
β‐globin
gene
has
many
alleles.

What
is
the
total
number
of
different
alleles
of
the
 β‐globin
 gene
that
could
be
carried
by
3
children
with
the
same
mom
&
dad.
_______
 
 26. Gerald
 and
 Lorna
 are
 both
 carriers
 of
 the
 autosomal
 recessive
 condition
 halitosis.
 If
 they
 have
 3
 children,
what
is
that
probability
that
two
will
be
affected
and
one
will
not,
regardless
of
order?
____
 
 
 27. A
 frog
 somatic
 cell
 contains
 approximately
 15
 picograms
 (pg)
 of
 DNA
 in
 the
 G1
 phase.
 
 How
 any
 picograms
of
DNA
are
expected
in
a
gamete
produced
by
this
individual?
______
pg
 
 
 
 
 
 
 
 
 
 ...
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This note was uploaded on 01/10/2010 for the course BIOLOGY biol2040 taught by Professor Tamarakelly during the Fall '09 term at York University.

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