Lecture 2. Thursday, August 31. Intermolecular interactions, triplet code and the amino acids

Lecture 2. Thursday, August 31. Intermolecular interactions, triplet code and the amino acids

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Restricted: For students enrolled in Chem130/MCB100A, UC Berkeley, Fall 2006 ONLY 1 John Kuriyan: University of California, Berkeley Chem 130/MCB 100A, Fall 2006, Lecture 2 We will now take a brief diversion to review the basic kinds of molecular interactions that are important for understanding RNA, DNA and proteins. Inter-Atomic Interactions -Except for chemical reactions, most interactions can be understood classically, i.e., without quantum mechanics -We shall study these in detail later (Chapter 6). For now, we deal with a qualitative discussion. 1. Van der Waals interaction - Most interatomic interactions arise due to electrostatics. - Even neutral atoms attract each other electrostatically:
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Restricted: For students enrolled in Chem130/MCB100A, UC Berkeley, Fall 2006 ONLY 2 When two such neutral atoms approach each other, the transient dipoles can stabilize each other:
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Restricted: For students enrolled in Chem130/MCB100A, UC Berkeley, Fall 2006 ONLY 3 The hard sphere like energies at close contacts is one of the defining elements of DNA, RNA and protein structure: - Why RNA cannot form standard β -form (Watson- Crick) DNA. -
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This note was uploaded on 01/12/2010 for the course MCB 100A taught by Professor Kuryian during the Fall '09 term at Berkeley.

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Lecture 2. Thursday, August 31. Intermolecular interactions, triplet code and the amino acids

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