{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

lecture14 - Complex III IV Substrate level phosphorylation...

Info iconThis preview shows pages 1–23. Sign up to view the full content.

View Full Document Right Arrow Icon
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
ΙΙΙ
Background image of page 2
Complex III
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Background image of page 4
IV
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
ΙΙ
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Background image of page 10
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Substrate level phosphorylation
Background image of page 12
The Proton Gradient
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
1. How are protons pumped 2. What is the nature of the gradient/energetics 3. How many protons are pumped 4. How is the gradient maintained 5. How do the protons return to the matrix 6. How is that return coupled to ATP synthesis 7. How many ATP are produced per electron pair 8. How can the system be inhibited/studied
Background image of page 14
Each carrier a stronger oxidizing agent-- Each step, negative free energy-- Complex I -18kcal/mole Complex II - 4kcal/mole Complex III -10kcal/mole Complex IV -27kcal/mole
Background image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Background image of page 16
ADP + Pi ATP Η + Η + Η + Η + Η + Η +
Background image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
1. How are protons pumped 2. What is the nature of the gradient/energetics 3. How many protons are pumped 4. How is the gradient maintained 5. How do the protons return to the matrix 6. How is that return coupled to ATP synthesis 7. How many ATP are produced per electron pair 8. How can the system be inhibited/studied
Background image of page 18
Background image of page 19

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
NADH FADH 2 CoQH 2 H 2 O
Background image of page 20
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}