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Lecture 11 - Lecture 11 Eukaryotic Transcription Eukaryote...

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Lecture 11 Eukaryotic Transcription
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Figure 1.19 The Biology of Cancer (© Garland Science 2007) Eukaryote Trxn. Is dominated by positive control Many factors needed (necessary) to start
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DNA (stretched and lined up end to end) in 23 pairs of chromosomes would measure ~2 meters Packaging solution: Chromatin is a complex of DNA and protein Genome: all chromosomes in an organism Chromosome: spooled string of genes in one unit Gene: linear sequence of nucleotides that make a functional product Nucleotide: smallest information unit Eukaryotic Transcription is controlled by chromosome structure Packaged DNA is often Transcriptionally Silent Oncogenes--sometimes aberrant activation
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Figure 1.17a The Biology of Cancer (© Garland Science 2007) Eukaryotic mRNA must be assembled from long precursors (SPLICING)
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Products of Transcription by RNA Polymerase Messenger RNA (mRNA) serves as temporary copy of genes that is used as a template for protein synthesis Synthesized by RNA pol II
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Figure 1.17b The Biology of Cancer (© Garland Science 2007)
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