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126 Review questions for final

126 Review questions for final - Review questions for L6-9...

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Review questions for L6-9 L6: repair and regeneration 1. Describe the process from neurodengeneration after axon injury. 2. What are the three types of neural repair mentioned in the text book? Describe them briefly. 3. What is Henry Head’s regeneration experiment? How was it done and what is the conclusion? 4. Can peripheral nerve regenerate? Is so, how and what’s the cellular mechanisms? 5. Why does a peripheral nerve regenerate better if it is crushed than if it is cut? 6. What happens to the denervated NMJ? How is the reinnervation achieved? 7. What are Schwann cells’ role in peripheral regeneration? 8. Can CNS neurons intrinsically regenerate? Describe an earlier experiment testing this? 9. How is the regeneration specificity achieved? Describe an experiment performed on this. 10. What are the three ways of CNS damage? What happens in each case? 11. Why do axons regenerate so much more successfully in the PNS than CNS? Or what prevent CNS regeneration and repair?
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