Slide2 - 3 Fig.7-31 Histone tails stabilize 30 nm fiber...

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1/3/10 1 Fig. 2-5 Nucleotides are connected by phosphodiester bonds nucleoside nucleotide base 5’ 3’ Fig. 6-3 Double stranded DNA is antiparallel Figs. 6-1 and 6-11 B form DNA is a right-handed helix with major and minor grooves More base atoms are exposed in major groove http://www.albany.edu/~achm110/bdnagrooveandwc.html (see also Figure 6-10 in Watson)
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1/3/10 2 Fig. 7-17 EM images of interphase and M phase DNA Fig.7-27 Histone H1 binds to DNA and core histones Fig. 7-22 Nucleosome structure Fig. 7-17 EM images of 10 nm and 30 nm chromatin fibers (‘beads-on-string’)
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Unformatted text preview: 3 Fig.7-31 Histone tails stabilize 30 nm fiber Davey et al (2002) Journal of Molecular Biology, 319:1097-1113 The tail of histone H4 (arrow) can link one nucleosome to another, but not when it is acetylated on lysine 16. Fig.7-35 Nucleosome remodeling activities (SWI/SNF can catalyze both activities) Fig.7-7 Centromeres essential for chromosome segregation 1/3/10 4 Heterochromatin and euchromatin H E http://www.bu.edu/histology/p/20104ooa.htm As of 2005, 100 gigabases of sequence information in GenBank (100 billion bases) http://www.ncbi.nlm.nih.gov/ Genbank/genbankstats.html...
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