Chapter 2.5 - 2.7 - BE 421 2. 2.1. 2.2. 2.3. 2.4. 2.5. 2.6....

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28 BE 421 2. KINETICS AND STOICHIOMETRY OF CELLULAR GROWTH 2.1. Introduction: review of exponential growth 2.2. Substrate limited growth 2.3. Growth stoichiometry 2.4. Kinetic and stoichiometry of bioproduct synthesis 2.5. Prediction of stoichiometry based on black box models 2.6. The respiratory quotient 2.7. More complex situations: Crabtree effect and limited respiratory capacity 29 Y' N/S = -s 3 + x 3 X/S O/S 1 4 ( ! s - ! x - ! p P/S ) ( ! i 4 + i 1 - 2 i 2 3 i 3 ) ( " i 1 2 i 1 3 2 i 3 ) CH s 1 O s 2 N s 3 + Y' O 2 NH 3 x 1 O x 2 N x 3 p 1 O p 2 C/S CO 2 W/S H 2 O Les bilans élémentaires permettent de calculer tous les coéfficients en fonction de deux d ! entre eux, par exemple en fonction de Y ! x/s et Y ! p/s : i = s, x, ou p) " s " x " p Black Box Model for Growth Stoichiometry No of yields: 6. No of elemental balances: 4. If 2 of the yields are known, the others may be computed by elemental balancing. If, e.g., Y' X/S and Y' P/S are known: Definition of the degree of reduction ! i For a compound S of the elemental composition C H S 1 O S 2 N S 3 " S # 4 + s 1 - 2s 2 - 3s 3 Analogously for ! P and ! X
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30 Elemental formulae, C-molar mass and degree of reduction of dry biomass reduction of dry biomass 31 1.
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This note was uploaded on 01/19/2010 for the course FSH BE223 taught by Professor Ursvonstockar during the Spring '08 term at Dublin City University.

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Chapter 2.5 - 2.7 - BE 421 2. 2.1. 2.2. 2.3. 2.4. 2.5. 2.6....

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