HIV-AIDS_110308

HIV-AIDS_110308 - HIVandAIDS Biology301 Fall2008 Overview...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
HIV and AIDS Biology 301 Fall 2008
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Overview What is HIV? What is AIDS? Global Prevalence Symptoms Biological Mechanisms Diagnosis Treatment and Prevention Case Studies
Background image of page 2
What is HIV? H uman I mmunodeficiency  V irus Retrovirus = has an RNA  GENOME. Size = 120 nm (60x smaller  than a RBC) Transmission Routes: Enters blood stream through  colonic or genital mucosal  linings Sexual contact Mother-to-child transmission Pregnancy Delivery Breastfeeding Contact with infected blood  and other body fluids Shared injection needles Contaminated skin-cutting  tools
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
What is HIV? Anatomy of HIV Lipid Membrane (or  Envelope): gp120 —docking protein,  helps virus ATTACH to host  cell membrane. gp41 —transmembrane  protein, helps virus ENTER  through host cell membrane. Matrix —provides structure and  protection for the virus. Capsid Composed of  p24 —a protein  used to detect presence and  replication of HIV. RNA —2 copies of single- stranded RNA. Reverse Transcriptase makes DNA from RNA Integrase —integrates the  new viral DNA into host cell  DNA. Protease —cleaves newly-
Background image of page 4
What is AIDS? A cquired I mmunoD eficiency  S yndrome Caused by HIV infection. Not all HIV-positive patients have  AIDS. Occurs when the body’s defenses  (the immune system) are  diminished. This leads to many  OPPORTUNISTIC INFECTIONS. AIDS defining Diagnosis: CD4 count of less than 200  (normal is 800 or more) One of 26 opportunistic 
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Global Prevalence of HIV-AIDS Region children  living  with HIV/ AIDS children  newly  infected Adult  prevalen ce* Deaths  of  children Sub- Saharan  Africa 22.0  million 1.9  million 5.0% 1.5  million
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/19/2010 for the course BIOL 301 taught by Professor Kocache,m during the Spring '08 term at George Mason.

Page1 / 17

HIV-AIDS_110308 - HIVandAIDS Biology301 Fall2008 Overview...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online