BB lecture 12-4-09 - Final exam 50405 (10AM class) Tuesday...

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Unformatted text preview: Final exam 50405 (10AM class) Tuesday 12-15-09 9 AM-12 noon PAI 3.02* *Painter Hall Chapter 18 (pp.376-377) Gene expression and cancer (concluding) ADDED: Chapter 19 Figure 19.6 (p.386) Learning objectives: Describe what is meant by the multistep model of cancer development. Recognize how an inherited predisposition can contribute to cancer Know the difference between the lytic cycle and lysogenic cycle of viruses The Multistep Model of Cancer Development More than one somatic mutation is generally involved About a half dozen DNA changes must occur for a cell to become fully cancerous These changes usually include at least one active oncogene and mutation or loss of several tumor-suppressor genes The development of cancer is not a fast process, but an accumulation of changes in a number of different cancer protection genes over a persons lifespan . why the development of cancer may take a long time and is more commonly seen in older people Fig. 18-22a Colon Colon wall Normal colon epithelial cells Colorectal cancer, with 135,000 new cases and 60,000 deaths in the United States each year, illustrates a multistep cancer path Colon...
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This note was uploaded on 01/20/2010 for the course BIO 50415 taught by Professor Batterton during the Spring '09 term at University of Texas at Austin.

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BB lecture 12-4-09 - Final exam 50405 (10AM class) Tuesday...

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