{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

SubElimDecMap - N 1 E1 predominate S N 1/E1 Very Weak Base...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Substitution/Elimination Decision Map Primary Alkyl Halide Methyl Halide Allylic and Secondary Alkyl Halide Tertiary Alkyl Halide E2 S N 1/E1 Very Weak Base ? S N 2 t BuOK ? Yes E2 No S N 2 Yes No For S N 2, Remember Chiral Center InVERSiON For E2, Remember anti-periplanar and Zaitsev For S N 1, Remember Chiral Center Scrambling For E1, Remember Zaitsev Note: With Very Weak Bases, S N 2 can compete here, but for the purposes of this class, assume S
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: N 1 / E1 predominate. S N 1/E1 Very Weak Base ? Yes Very Strong Base ? Yes E2 No S N 2 * * (An allylic halide has a halogen on a carbon adjacent to a C=C bond) ** ** Note: If tBuOK is the very strong base, an appreciable amount of a non-Zaitsev product can be formed because the bulky tBuOK will tend to react with the most accessib le H atom. No...
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online