Lecture6_Prok gene reg

Lecture6_Prok gene reg - Gene Regulation in Prokaryotes...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
Gene Regulation in Prokaryotes •Regulation basics in bacteria • promoters and proteins • sigma factors • activated vs repressed • examples: ! trp operon ! lac operon ! lux operon
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Two general kinds of operons: • repressible – txn* usually on but can be inhibited when a specific small molecule binds to a regulatory protein ( ex. trp operon) • inducible – txn* usually off but can be stimulated when specific small molecule interacts with a regulatory protein (ex. lac or lux operon ) * Note: txn = transcription
Background image of page 4
1 promoter = 1 mRNA = several genes = several proteins Recall: • Prokaryotic genomes have operon structure - functional clustering of genes • Operon - entire stretch of DNA needed for enzyme production for this pathway (operator, promoter, genes they control) • Allows for coordinate regulation Operon Promoter Operator Genes RNA
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/20/2010 for the course BIMM 100 taught by Professor Pasquinelli during the Spring '06 term at UCSD.

Page1 / 12

Lecture6_Prok gene reg - Gene Regulation in Prokaryotes...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online