ch369_f09_class3_notes

ch369_f09_class3_notes - Today s pl an - A f ew m nut es wi...

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Today’ s pl an - A f ew m i nut es wi t h am i no aci ds and pr ot ei ns. Then, on t o chapt er 3, “ Fr om Genes t o Pr ot ei ns” .
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Pr ot ei ns ar e pol ymer s of am i no aci ds. Si ngl e am i no aci d. “ R” gr oup i s di f f er ent , dependi ng on a. a. t ype. 20 di f f er ent am i no aci d t ypes commonl y occur i n pr ot ei ns.
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Exampl es of am i no aci ds: al ani ne phenyl al ani ne ser i ne
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Am i no aci ds ar e l i nked by pept i de bonds t o f or m pr ot ei ns. Al ani ne, ser i ne, phenyl al ani ne. Li nked t oget her by pept i de bonds. pept i de bond Pr ot ei ns t ypi cal l y cont ai n hundr eds of a. a. l i nked t oget her .
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Exampl es of pr ot ei ns: Myogl obi n bi nds oxygen. Ker at i n i s a f i br ous pr ot ei n, f ound i n hai r , f i nger nai l s, t or t oi se shel l s, et c. Pr ot ei n f unct i on depends on i t s st r uct ur e; St r uct ur e depends on t he am i no aci d
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Am i no aci ds. Ei t her way i s OK. Text book l i kes t hi s. I l i ke t o dr aw t hem l i ke t hi s.
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( or non- pol ar ) ( or hydr ophi l i c)
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Become f am i l i ar wi t h t he 20 am i no aci ds t hat commonl y occur i n pr ot ei ns. 3 l et t er abbr evi at i ons, pr oper t i es. Chapt er 4 i s al l about pr ot ei ns.
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“ Fr om Genes t o Pr ot ei ns” Chapt er 3 of t ext book. Cent r al dogma of mol ecul ar bi ol ogy:
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A f ew wor ds about DNA & RNA.These ar e pol ymer s. Component s of DNA & RNA: DNA: adeni ne ( A) , guani ne ( G) , cyt osi ne ( C) , t hym i ne ( T) . RNA: adeni ne ( A) , guani ne ( G) , cyt osi ne ( C) , ur aci l ( U) . A & G have a si m i l ar pur i ne r i ng st r uct ur e.
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C, T & U have a si m i l ar pyr i m i di ne r i ng st r uct ur e. Ur aci l ( U) i s a component of RNA. Looks l i ke t hym i ne, but wi t h met hyl gr oup.
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Nucl eosi des - A base at t ached t o a r i bose sugar r i ng. ( base = A, C, G, T, U) Ri bose ( RNA) 2- deoxyr i bose ( i n DNA)
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adenosi ne ( f ound i n RNA) Exampl es of nucl eosi des: deoxyadenosi ne ( f ound i n DNA)
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Nucl eot i des have one or mor e phosphat e gr oups at t ached.
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ch369_f09_class3_notes - Today s pl an - A f ew m nut es wi...

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