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ch369_f09_tca_notes - Summary of glycolysis Can you...

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Summary of glycolysis: Can you describe, briefly, in words: What is glycolysis? What is the overall point of glycolysis? What’s the pentose pathway good for? What’s gluconeogenesis?
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Chapter 11 - The citric acid cycle Things I like to know when trying to understand something new in metabolism: Where does the process occur? What is the purpose of the process? The citric acid cycle naturally follows glycolysis, since it describes something that pyruvate can be used for! Known as the “ citric acid cycle ” or “ Krebs cycle ” or tricarboxylic acid cycle ” or “ TCA cycle ”.
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In eukaryotic cells, the citric acid cycle happens in the mitochondria. mitochondria A eukaryotic cell Where does the citric acid cycle occur?
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Before entering the citric acid cycle, the pyruvate generated by glycolysis is converted to “acetyl coenzyme A” by an enzyme called the “pyruvate dehydrogenase complex” (abbreviated PDC or PDH). Overall reaction: pyruvate + NAD + + CoA =======> acetyl CoA + NADH + CO 2 Do you remember what these things are? pyruvate dehydrogenase complex
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Coenzyme A and acetyl-CoA. CoA Acetyl CoA
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pyruvate + NAD + + CoA =======> acetyl CoA + NADH + CO 2 pyruvate dehydrogenase complex The pyruvate dehydrogenase complex (PDC) is enormous!
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