Topic 9 Talaro7th-Chapter 15

Topic 9 Talaro7th-Chapter 15 - Chapter 15 [Talaro]...

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Chapter 15 [Talaro] – Adaptive, Specific Immunity & Immunizations I. Classification of Acquired/Adaptive Immunity [Fig. 15.1] A. Natural vs. artificial B. Active vs. passive II. Overview of adaptive immunity [Fig. 15.2] A. Antigen (Ag) = any molecule or agent that activates an animal’s adaptive immune response [see also Fig. 15.8] III. Lymphocytes [Figs. 14.7 (pg. 427 – 428), 15.4] A. B cells: mature in bone marrow (produce antibodies; basis of humoral immunity) B. T cells: mature in thymus (produce cytokines that coordinate immune responses; participate in cell-mediated immunity) IV. How does the immune systems distinguish self from nonself? A. Cell surface markers/receptors: MHC = HLA [Fig. 15.3] 1. Class I MHC glycoproteins found on the surface of almost all nucleated cells 2. Class II MHC glycoproteins found on some the surface of certain leukocytes (macrophages, dendritic cells, B cells) B. Lymphocyte receptors [Fig. 15.4] 1. B cells: immunoglobulin (Ig) receptors 2. T cells:
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This note was uploaded on 01/23/2010 for the course BIO 307D taught by Professor Moore during the Fall '09 term at University of Texas at Austin.

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Topic 9 Talaro7th-Chapter 15 - Chapter 15 [Talaro]...

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