Topic 3 Chp9_Basic GeneticsP

Topic 3 Chp9_Basic GeneticsP - TalaroChapter9...

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Talaro – Chapter 9 Basic Genetics: DNA, RNA, Protein
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Role of genetic  information (DNA) in  the life of a cell Panel A:  Between generations DNA replication precedes  cell division Panel B:  Within a cell  Gene expression of DNA  code produces RNA RNA code is converted to  proteins Proteins provide cell  cell functions Panel A Panel B
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A Cell’s Instruction Manual is contained  within its Chromosomes Replicated chromosome (L) is made up of double-stranded DNA (R)
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Genome = Total of all of a cell’s  chromosomes DNA content => genotype Genotype expression => observable outcome phenotype
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Genomes of Microorganisms are smaller To carry out functions that maintain the life of a cell/microbe:  DNA is copied into RNA RNA is decoded into protein
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Nucleotides:  Building Blocks for DNA  and RNA Base = chemical molecule  containing Nitrogen  Prefix:  de oxy = w/out oxygen Carbons on sugar ring are numbered, 1’ – 5’
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Nitrogen-containing bases
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In double-stranded (ds) DNA, 2 strands  are  antiparallel Nomenclature based on  deoxy ribose  ring – each carbon position has a number  Nucleotides have  5’- end 3’- end 5’- end of polynucleotide has ‘free’ PO 4  group 3’-end of polynucleotide has ‘free’ OH group  Order of nucleotide bases = DNA code  2 polynucleotide strands are held  together by hydrogen bonds  Opposites attract:  (+) . . . (-)
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Topic 3 Chp9_Basic GeneticsP - TalaroChapter9...

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