Topic 6 Chp6_GenVirusP - TalaroChapter6 Viruses...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
Talaro Chapter 6 Viruses 
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Viruses – ‘Smallest’ of the Small From:  Cowan & Talaro, Microbiology:  A Systems Approach (2 nd  ed), McGraw-Hill, 2009
Background image of page 2
Overview of Viruses Obligate intracellular parasites; replicate inside cells  lack metabolic capacity use cellular machinery to replicate nucleic acids, proteins use cell energy (ATP, GTP) Infect  all  known cellular  life forms - bacteria - fungi - protozoa - algae - arthropods  - plants - animals
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Overview of Viruses Viral structure nucleic acid genome [DNA  or  RNA] protective protein shell [ capsid  made of protein  subunits called capsomeres] some  animal viruses have a phospholipid bilayer  around capsid [ envelope ]
Background image of page 4
Generalized animal virus structure Viral genomes [DNA or RNA] - double-stranded or single-stranded DNA - double-stranded or single-stranded RNA
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Capsids have different shapes  [reflect ‘simple’ geometric forms] Icosahedral capsid (made of capsomeres) has 20 sides enclosing viral genome Size of capsid reflects relative size of viral genome
Background image of page 6
Some animal  viruses have an  envelope   around viral nucleocapsid* Phospholipid  bilayer  Derived from ‘modified’ host cell membranes  Envelope contains viral proteins ( spikes ) by capsid
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Generalized Viral Replication Cycle [5 basic steps] Adsorption  / Attachment - proteins on virus surface  bind to  receptors  on host cell
Background image of page 8
All cells have surface molecules that allow them  to interact with other cells or their environment.
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/23/2010 for the course BIO 307D taught by Professor Moore during the Fall '09 term at University of Texas at Austin.

Page1 / 34

Topic 6 Chp6_GenVirusP - TalaroChapter6 Viruses...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online