projectideas

projectideas - Harvard-MIT Division of Health Sciences and...

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Some Project Ideas Optimize Single Cell Traps The single-cell traps you used in lab were de- signed as a prototype, with little effort put in to optimizing the design for efficiency of trapping (as you probably noticed). One project idea is to identify the parameters that affect trapping efficiency to allow trap design to be optimized for individual cell types. This project would involve fab- ricating a series of traps with slightly different conFgurations (trap size, trap spacing, uniformity, etc.) and testing each for efficiency of trapping. Design Microfabricated Valves One signiFcant challenge in making prac- tical microfluidic devices is controlling the flow of fluid using valves. A variety of valve designs have been proposed and made. This project would involve testing various designs to Fnd the best one, and potentially design- ing a new type of valve. Coulter Counter A common application of microfluidic devices is cell count- ing. As you read in the paper, this step is often done visually, using a microscope and a camera. An alternate technique is to build a Coulter
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projectideas - Harvard-MIT Division of Health Sciences and...

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