Massachusetts Institute of Technology Harvard-MIT Division of Health Sciences and Technology and Department of Electrical Engineering and Computer Science HST.410J/6.07J Projects in Microscale Engineering for the Life Sciences Homework Assignment #4 Issued: March 6, 2007 Due: March 13, 2007 For this week’s homework, please read the Rodriguez paper that is posted on our website ( http://umech.mit.edu/6.07J/index.php in the Handouts section). Write short para-graphs addressing each of the following issues (which we will also discuss in class on March 8): 1. Discuss the strengths of the microchip counter for counting CD4 cells over previous tech-niques. What are its weaknesses? Is this technique a useful application of micro-scale engineering? Why or why not? 2. Does the microchip counter work as effectively as previous cytometry techniques mentioned by the authors? What evidence do the authors present to show that the microchip counter works effectively? Are you convinced by their arguments? 3.
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