casting_masters

casting_masters - Harvard-MIT Division of Health Sciences...

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Casting Masters Masters for casting microfluidic channels are typically made from thin silicon wafers, and are quite fragile. Moreover, masters tend to lose their patterns over time, and are difficult to modify to make variations on a single design. Here we demonstrate a technique for using an existing master to create a new master out of plastic. This new master is sturdy and can be easily modified (e.g., with wax or modeling clay). Moreover, multiple plastic masters can be made from a single silicon mapster, allowing each group of students in the class to have their own master. The first step is to use the silicon master to cast a PDMS device such as the one shown below (link goes to larger image). In this case, metal cylinders were used during casting to create holes for inserting the plastic cylinders. Rather than bonding the device to a glass slide as shown in the above image, though, the device is placed in the bottom of a plastic tray channel-side up. A quick-hardening plastic is poured over the device and allowed to solidify. The plastic takes the complementary
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casting_masters - Harvard-MIT Division of Health Sciences...

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