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Unformatted text preview: r o (Points: 0.5) Which of the following is a Phase I reaction in the liver? c. oxidation (Points: 0.5) Drug X is metabolized by CYP2C9 to an inactive metabolite. Following administration of Drug Y which is a potent and irrevers a. Increase above the minimum effective concentration to result in drug toxicity. (Points: 0.5) Which of the following Phase II reaction results in more nonpolar metabolites? Sheet1 Page 2 c. acetylation (Points: 0.5) Which of the following statement describing biliary excretion is FALSE? d. Drugs that are excreted in bile generally have molecular weights less than 300 Da. (Points: 0.5) Which part of the nephron is involved in the active secretion of drugs resulting in their elimination from the body? b. proximal tubule...
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- Spring '10
- pH, Drug toxicity, weak base drug