phar 241 quiz 1 answers

phar 241 quiz 1 answers - r o (Points: 0.5) Which of the...

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Sheet1 Page 1 Phar 241 Quiz 1 - 2009 Questions: 10 (Points: 0.5) Which of the following statement correctly describes paracellular transport of drugs with sizes smaller than the junctions betw e c. Paracellular transport is not determined by drug lipophilicity. (Points: 0.5) The rate and extent of drug absorption across a biological membrane is governed by which one of the following factors? c. Its physicochemical properties. (Points: 0.5) A weak base drug has a pKa=4. At the stomach pH 9 2, which of the following statement is correct? d. The concentration of the ionized form of the drug is 100-fold higher than the nonionized form of the drug. Save Answer (Points: 0.5) Which of the following route of administration is susceptible to first-pass metabolism? b. oral (Points: 0.5) Which of the following statement correctly describes drug binding to plasma proteins? c. Drug dosage adjustment is always necessary under pathological conditions that result in changes in the levels of plasma p
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Unformatted text preview: r o (Points: 0.5) Which of the following is a Phase I reaction in the liver? c. oxidation (Points: 0.5) Drug X is metabolized by CYP2C9 to an inactive metabolite. Following administration of Drug Y which is a potent and irrevers a. Increase above the minimum effective concentration to result in drug toxicity. (Points: 0.5) Which of the following Phase II reaction results in more nonpolar metabolites? Sheet1 Page 2 c. acetylation (Points: 0.5) Which of the following statement describing biliary excretion is FALSE? d. Drugs that are excreted in bile generally have molecular weights less than 300 Da. (Points: 0.5) Which part of the nephron is involved in the active secretion of drugs resulting in their elimination from the body? b. proximal tubule...
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phar 241 quiz 1 answers - r o (Points: 0.5) Which of the...

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